I have run a reef quarantine setup for two years and quarantined every fish and invert before it hit my 120 gallon display. Two outbreaks in my first year of reefkeeping taught me that quarantine is cheaper than a tank wipe. Here is the kit I would buy again, and the routine that works.

Quick gear comparison

GearPurposePick
Quarantine tank20 to 40 gallons, bare bottomAqueon 20 gallon Long
Sponge filterPre-cycled, no biomediaAquaClear 30 sponge filter
Heater100 to 150 watts, controller-readyEheim Jager 150W heater
Med kitCopper, prazi, formalinHanna Copper Checker
PVC hidesStress reductionPVC fittings starter kit

1. The tank - 20 gallon long, bare bottom

A 20 gallon long gives you horizontal swim room without consuming half a closet. I run mine bare bottom because sand binds copper and complicates medication dosing. Cleanup is a single siphon pass. The Aqueon 20 Long has the right dimensions for a tang or large angelfish to acclimate in.

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2. Filtration - sponge filter only

A pre-cycled sponge filter is the only biological filtration that survives a copper course. I keep a spare sponge in my sump at all times so quarantine is ready in 30 minutes when a fish ships. Hang-on-back filters with ceramic media get destroyed by copper and become useless.

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3. Heater and temp control

A 150W Eheim Jager holds temperature in a 20 long without overshooting. I pair it with an inkbird controller to prevent stuck-on disasters. Quarantine temperature ramping is part of the protocol: 80 to 82 F speeds the ich lifecycle, shortening total treatment time.

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4. Medication kit

The core stack: chelated copper for ich and velvet, praziquantel for flukes, and formalin for stubborn flukes if prazi fails. The most important purchase is a Hanna Copper Checker. Test strips lie about copper level and stripping out at 1.8 ppm versus 2.5 ppm is the difference between treatment and a dead fish.

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5. Hides - PVC fittings

Stress drops disease defenses. A box of black PVC fittings gives every new fish three or four caves to choose from. Cheap, easy to clean, and they do not absorb copper.

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My 6-week quarantine routine

  • Week 1: Acclimate fish, observe for 7 days, no meds. Watch for flashing, white spots, rapid breathing.
  • Week 2-3: Begin chelated copper ramp to 2.0 to 2.5 ppm over 4 days. Hold 14 days. Test copper daily with the Hanna.
  • Week 4: Strip copper with cuprisorb or large water changes. Begin prazi 5-day course for flukes.
  • Week 5: Observation, fresh water changes, food trials. Heavy feeding to put weight back on.
  • Week 6: Final 7-day observation. If clean, transfer to display.
  • Always quarantine inverts separately; copper is fatal to shrimp, snails, and corals.

How to set up your quarantine

  • Keep the sponge filter in your display sump full-time so it stays cycled.
  • Use white buckets and a dedicated siphon for quarantine to avoid contaminating the display.
  • Photograph the fish on arrival. Photos reveal spots and erosion that look subtle in person.
  • Buy one extra heater. Quarantine heater failures are the most common cause of stalled treatment.
  • Write down your med schedule. Memory fails after a long day; a posted log does not.

Frequently asked questions

How long should new fish stay in quarantine?+

Four to six weeks. Two weeks is not long enough; many parasites cycle in 21 to 28 days, so shorter quarantines miss them.

Do I need to quarantine corals too?+

Yes. Coral quarantine for 76 days breaks the lifecycle of pests like AEFW and red bugs, even if the coral looks clean on arrival.

Independent video for additional perspective on Reef tank quarantine setup I run for every new fish.

Third-party YouTube content. Watch on YouTube.
CW
Author

Casey Walsh

Home, Kitchen & Pet Products Editor

Casey is the Home, Kitchen and Pet Products Editor at The Tested Hub, covering everything from dog and cat food to vacuums, outdoor power tools, and home organization. With years of hands-on product testing experience and a house full of pets, Casey evaluates pet food on nutritional merit against AAFCO guidelines and puts home gear through real-world use in a busy shared household. Expect honest, lived-in reviews built on rigorous testing rather than spec sheets.