Clear Care Plus -- Best for Monthly Biofinity Users
Monthly lens wearers carry more accumulated protein and lipid load than two-week or daily wearers, making peroxide the gold standard for end-cycle cleaning. Clear Care Plus strips deposits from Biofinity's silicone hydrogel surface more thoroughly than preserved multipurpose solutions. If you wait until week three or four to notice that your lenses feel cloudy or uncomfortable, the issue is almost certainly deposit buildup that Clear Care addresses better than any multipurpose formula. The required six-hour soak fits naturally into an overnight cleaning routine.
Check price on Amazon →Biofinity monthly lenses need a solution that handles silicone hydrogel materials over a 30-day cycle. These five picks keep them clean, comfortable, and clear.
Health disclaimer: Extended or monthly contact lens wear involves real eye health considerations. Consult your eye doctor about safe wear schedules and solution compatibility, particularly if you experience any redness or discomfort.
Biofinity lenses from CooperVision are made with Aquaform Comfort Science technology, a silicone hydrogel material that allows high oxygen transmission while retaining moisture without surface coatings. Monthly replacement means lenses spend up to 30 days accumulating tear film proteins and lipids. A solution capable of thorough cleaning at each removal cycle is critical to maintaining comfort and optical clarity through the full month.
| Product | Best For | Rating |
| — | — | — |
| Clear Care Plus | Deep clean monthly cycle | 4.8/5 |
| Biotrue Multipurpose Solution | Balanced everyday care | 4.7/5 |
| Opti-Free Puremoist | Moisture through long wear days | 4.6/5 |
| Bausch + Lomb Ultra | MoistureSeal for dry eyes | 4.6/5 |
| RevitaLens OcuTec | Preservative-sensitive wearers | 4.5/5 |
Our testing process
We compare every pick against the field on real specifications, certifications, and aggregated owner reviews. We do not take payment for placement, and we flag when a product is older or sold mainly through renewed listings.
Quick comparison
| Pick | Best for | Score | |
|---|---|---|---|
| Clear Care Plus -- Best for Monthly Biofinity Users | Check price | ||
| Biotrue -- Best All-Around Daily Option | Check price | ||
| Opti-Free Puremoist -- Best for Extended Wear Days | Check price | ||
| Bausch + Lomb Ultra -- Best for Dry Eye Combination | Check price | ||
| RevitaLens OcuTec -- Best for Sensitive Eyes | Check price |
Reviewed in detail
Clear Care Plus -- Best for Monthly Biofinity Users
Monthly lens wearers carry more accumulated protein and lipid load than two-week or daily wearers, making peroxide the gold standard for end-cycle cleaning. Clear Care Plus strips deposits from Biofinity's silicone hydrogel surface more thoroughly than preserved multipurpose solutions. If you wait until week three or four to notice that your lenses feel cloudy or uncomfortable, the issue is almost certainly deposit buildup that Clear Care addresses better than any multipurpose formula. The required six-hour soak fits naturally into an overnight cleaning routine.
Biotrue -- Best All-Around Daily Option
Biotrue's hyaluronan formula and tear-pH matching make it the most comfortable daily multipurpose solution for Biofinity lenses for most wearers. It cleans effectively, rinses cleanly, and does not leave a residue that interferes with Biofinity's inherent surface wettability. For wearers who do not want to commit to the six-hour peroxide soak cycle, Biotrue with a nightly rub-and-rinse technique offers the best balance of convenience and cleaning performance.
Opti-Free Puremoist -- Best for Extended Wear Days
Biofinity lenses are sometimes worn by people who want the extended wear option, which means their lenses may be in use for longer active hours than typical two-week lenses. Opti-Free Puremoist's HydraGlyde coating technology is designed specifically for silicone hydrogel lenses worn long hours. When Biofinity wearers remove lenses after a long continuous wear period and soak them in Puremoist, lenses tend to feel noticeably fresher when reinserted than after soaking in standard solutions.
Bausch + Lomb Ultra -- Best for Dry Eye Combination
B+L Ultra is built around MoistureSeal technology, a retention agent that bonds to the lens surface and maintains hydration through the storage and wear cycle. For Biofinity wearers who also deal with dry eye conditions, Ultra offers a solution-level intervention that complements the lens's own moisture retention properties. It is silicone hydrogel compatible and performs well for monthly lens schedules. It costs slightly more than standard options but the moisture benefit is meaningful for dry eye patients.
RevitaLens OcuTec -- Best for Sensitive Eyes
RevitaLens avoids some common preservative formulations that trigger reactions in sensitive wearers. For Biofinity users who have tried multiple solutions and still experience redness or a burning sensation on insertion, RevitaLens is a well-regarded gentler alternative. Its disinfecting efficacy meets FDA standards for contact lens solutions and it is compatible with Biofinity's material. It is available in twin packs that reduce cost per ounce for regular users.
How to choose
What to consider
For monthly lenses, cleaning thoroughness matters more than for short-cycle lenses. If you wear Biofinity for the full 30 days, use either a peroxide system nightly or a premium multipurpose solution with the rub-and-rinse technique. If you choose extended continuous wear, your eye doctor's guidance on care routine takes priority over general recommendations. Replace your case every three months and never top off old solution in the case; pour it out and use fresh solution every time.
What to consider
For toric Biofinity users, read our [best contact solution for Biofinity toric lenses](/articles/best-contact-solution-for-biofinity-toric-lenses) guide. If you are comparing across lens brands, see our [best contact solution for astigmatism](/articles/best-contact-solution-for-astigmatism) overview. For evaluation methodology, visit [methodology](/methodology).
Common questions
CooperVision does not mandate a single solution for Biofinity lenses but states compatibility with most standard multipurpose solutions for silicone hydrogel lenses. Biotrue, Opti-Free Puremoist, and Clear Care Plus are widely cited by Biofinity wearers and are compatible with the Aquaform Comfort Science material that Biofinity lenses are made from. Always confirm compatibility with your eye care provider.
Biofinity lenses are FDA-approved for up to six nights and seven days of continuous wear, but most eye care professionals recommend daily removal and cleaning for long-term eye health. Extended wear increases the risk of infection and hypoxia. When lenses are removed, they should always be cleaned and stored in fresh solution, never in water or dried out.
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