Health disclaimer: Contact lens care affects eye health directly. Consult your eye care provider before switching solution types, especially if you have dry eyes, allergies, or a history of eye infections.
Acuvue is one of the most prescribed contact lens brands in the world, covering everything from daily disposables to monthly silicone hydrogel lenses. Not every solution works equally well with every lens material, so choosing a compatible option matters for both comfort and lens longevity. These five solutions are well-regarded by Acuvue wearers and widely available without a prescription.
| Product | Price | Best For | Rating |
|---|---|---|---|
| Biotrue Multipurpose Solution | ~$12 | Everyday Acuvue care | 4.7/5 |
| Opti-Free Puremoist | ~$14 | All-day moisture retention | 4.6/5 |
| RevitaLens OcuTec | ~$13 | Sensitive eyes | 4.6/5 |
| Clear Care Plus | ~$16 | Deep clean and comfort | 4.8/5 |
| Complete Multi-Purpose Solution | ~$9 | Budget-friendly option | 4.3/5 |
Biotrue Multipurpose Solution — Top Pick for Acuvue Wearers
Biotrue is formulated at the same pH as natural tears, which makes it gentle for everyday use with Acuvue’s silicone hydrogel lenses. It uses a dual disinfectant system and includes hyaluronan, a lubricant naturally found in the eye, to help lenses stay moist throughout the wear cycle. Acuvue Oasys and Acuvue Vita users frequently cite Biotrue as their go-to because it does not leave a residue that dulls lens clarity. For most standard Acuvue wearers without significant sensitivities, Biotrue is a reliable, everyday-use pick.
Opti-Free Puremoist — Best for All-Day Moisture
Alcon’s Opti-Free Puremoist uses a HydraGlyde moisture matrix technology that coats lenses to help maintain surface moisture over extended wear periods. Acuvue wearers who work long hours in front of screens or in air-conditioned environments often find this solution helps reduce that late-day dryness. The disinfecting system handles bacteria and Acanthamoeba effectively. It does contain preservatives, so wearers with preservative sensitivity should consider a peroxide option instead.
RevitaLens OcuTec — Best for Sensitive Eyes
RevitaLens uses a dual biocide system with PHMB-free formula, making it a gentler choice for wearers who have had reactions to older solution formulations. Its cleaning ability is strong enough for silicone hydrogel lenses while being mild on the ocular surface. Acuvue Oasys 1-Day and Acuvue Define wearers who keep a backup pair have reported good results with RevitaLens for extended overnight storage. The solution also performs well in lens cases that are cleaned and replaced regularly.
Clear Care Plus — Best Deep Clean
Clear Care Plus from Alcon is a 3% hydrogen peroxide solution that breaks down protein and lipid deposits more thoroughly than most multipurpose formulas. The platinum disc in the included case neutralizes the peroxide over a six-hour soak, leaving lenses in pure saline ready for insertion. For Acuvue Oasys for Astigmatism wearers or anyone experiencing buildup or end-of-day discomfort with multipurpose solutions, stepping up to a peroxide system often makes a noticeable difference in comfort and lens clarity.
Complete Multi-Purpose Solution — Best Budget Pick
AMO’s Complete Multi-Purpose solution covers the basics: cleaning, rinsing, disinfecting, and storing. It works with Acuvue lenses and is widely available at drugstores. The price per ounce is lower than premium options, making it a practical choice for wearers on a budget or those who need a backup bottle. It does not include the advanced moisture matrix additives of premium formulas, so wearers with dry eye symptoms may find it less comfortable over a full day. For part-time wearers or those using daily disposables who just need a rinse solution, it is a solid value.
How to Choose Contact Solution for Acuvue Lenses
First, identify your Acuvue lens type. Acuvue Oasys and Vita are silicone hydrogel monthlies that benefit from solutions with strong protein removal. Acuvue Moist dailies are thrown away each day so storage solution is less of a concern. Next, assess your comfort level: if your eyes feel dry or irritated by end of day, look for solutions with hyaluronan or HydraGlyde-type moisturizing agents, or switch to a peroxide system. Avoid any solution not listed as compatible with silicone hydrogel materials. Always follow the full soak time recommended on the label.
For related guidance, read our picks for best contact solution for Acuvue Oasys for Astigmatism and best contact solution for red eyes. See our methodology for how we select and rank products.
Frequently asked questions
What contact solution does Acuvue recommend?+
Acuvue does not mandate a single solution, but Johnson & Johnson (the maker of Acuvue) recommends multipurpose solutions that are compatible with silicone hydrogel materials. Solutions like Biotrue, RevitaLens, and Opti-Free Puremoist are widely used by Acuvue wearers. Always check the lens packaging or ask your eye care provider for guidance specific to your lens type.
Can I use Clear Care with Acuvue lenses?+
Yes. Clear Care hydrogen peroxide solution is compatible with most Acuvue lenses including Oasys and Vita. Peroxide systems tend to leave no preservative residue, which can help wearers who experience irritation with multipurpose solutions. The key requirement is completing the full six-hour neutralization cycle before inserting lenses. Never insert lenses soaked in un-neutralized peroxide solution.